Toxoplasmosis

  • Posted: April 30th, 2012 - 2:33pm by Doug Powell

    Thanks to our French friend, Albert Amgar, for forwarding this item.

    On 15 November 2010, 3 confirmed cases of toxoplasmosis of the same family were reported to the Midi-Pyrénées Regional Health Agency. A collective outbreak of food poisoning was suspected with regard to the single common meal taken on 3 October 2010 that included undercooked lamb’s leg. Clusters of toxoplasmosis cases are rare; therefore, investigations on the episode were conducted.

    Epidemiological, clinical and serological data were collected from the participants in the meal. Genotyping of the strain isolated in the suspected food was performed as well as a traceability investigation.

    All five sensitive people of the seven persons exposed during the meal had a recent uncomplicated evolutionary toxoplasmosis (attack rate 100 %; mean age 21 years). DNA genotyping in the frozen half lamb’s leg revealed a type II. The farm of origin of the lamb could not be identified.

    Our investigations contributed to describe a Toxoplasma food poisoning limited in size, and to determine the origin of the contamination. However, other cases may have gone unnotified, considering the infection is usually asymptomatic. Toxoplasma foodborne illnesses are poorly documented and information on the possibility of contamination due to insufficiently cooked lamb meat should be spread more widely.

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  • Posted: January 7th, 2012 - 4:20am by Doug Powell

    When toxoplasma in pork ranked second in last year’s top 10 riskiest combinations of foods and disease-causing microorganisms at $1.2 billion a year, some wondered, what?

    Now the Brits have chirped in, saying much more needs to be known about Toxoplasma gondii in the country’s food and especially the impact on pregnant women.

    The UK Food Standards Agency’s (FSA) Advisory Committee of the Microbiological Safety of Food (ACMSF) is seeking stakeholder views on its draft report relating to toxoplasma in the food chain (available at http://www.food.gov.uk/multimedia/pdfs/consultation/criskprotoxoplasmafoodchain.pdf).

    According to the UK National Health Service (NHS), food sources include undercooked or raw meat, raw cured meat (including Parma ham, salami) and unpasteurised goat’s milk, and the infection can pass between humans from a pregnant woman to an unborn baby.

    Although toxoplasmosis usually only causes mild flu-like symptoms in adults, the ACMSF said it can be fatal to babies, and has been linked with associated jaundice, eye infections and seizures.

    The FSA’s scientific advisory committee was asked to consider whether current evidence indicates a food safety issue that needs to be addressed, what food sources could present a significant risk and identify further work needed on UK prevalence and foodborne sources of toxoplasmosis.

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  • Posted: April 28th, 2011 - 7:32am by Doug Powell

    chicken.therm_.jpg

    If policy types are going to focus resources, it helps to know where to get the most bang for the regulatory dollar.

    Researchers at the University of Florida Emerging Pathogens Institute have attempted to identify the Top 10 riskiest combinations of foods and disease-causing microorganisms.

    The report, Ranking the Risks: The 10 Pathogen-Food Combinations with the Greatest Burden on Public Health, lists the number of illnesses, costs, and overall public health burden of specific microbes in particular types of food. The list includes:

    Campylobacter in poultry — costs $1.3 billion a year
    Toxoplasma in pork — costs $1.2 billion a year
    Listeria in deli meats — costs $1.1 billion a year
    Salmonella in poultry — costs $700 million a year
    Listeria in dairy products — costs $700 million a year
    Salmonella in complex foods — costs $600 million a year
    Norovirus in complex foods — costs $900 million a year
    Salmonella in produce — costs $500 million a year
    Toxoplasma in beef — costs $700 million a year
    Salmonella in eggs — costs $400 million a year


    “The number of hazards and scale of the food system make for a critical challenge for consumers and government alike,” said Michael Batz, lead author of the report and head of Food Safety Programs at the Emerging Pathogens Institute. “Government agencies must work together to effectively target their efforts. If we don’t identify which pairs of foods and microbes present the greatest burden, we’ll waste time and resources and put even more people at risk.”

    Of these, the new report concludes that five leading bugs—Campylobacter, Salmonella, Listeria monocytogenes, Toxoplasma gondii, and norovirus – result in $12.7 billion in annual economic loss - with the Top 10 pathogen-food combinations responsible for more than $8 billion. That burden includes the cost of medical care and lost productivity from employee sick days, as well as the expense of serious complications or chronic disabilities that result from the acute illness or sometimes strike after acute illness goes away.

    Douglas Archer, associate dean for research at the UF Institute of Food and Agricultural Sciences who reviewed the report, told The Gainesville Sun, "You can't inspect away foodborne illnesses.”

    Of course, a farming rep told the Sun, food producers have to be diligent in ensuring food safety, but the public also has to play a role.

    Frankie Hall, director of agricultural policy for the Florida Farm Bureau said, producers can do a good job only to have the person who takes the food home handle it improperly, adding, "There is responsibility for food safety when you get it back to the home.”

    J. Glenn Morris, the director of the Emerging Pathogens Institute at the University of Florida and one of the authors of the study told the Washington Post that policymakers at the USDA, which regulates meat, poultry and some egg products, and the FDA, which oversees the rest of the food supply, should consider the economic burden on society when deciding how to direct food safety resources, adding, “You can begin to use these more sophisticated analytic tools, which can serve as the basis of spending public dollars in terms of food safety.”

    The report, which was supported by a grant from the Robert Wood Johnson Foundation, includes the following key findings and recommendations for food safety officials:

    • Poultry contaminated with Camplylobacter bacteria topped the list, sickening more than 600,000 Americans at a cost of $1.3 billion per year. Salmonella in poultry also ranks in the Top 10, with $700 million due to costs of illness. Infections with these microorganisms can cause acute illness such as vomiting but also can lead to hospitalization or death. Campylobacter infection can also cause paralysis and other neuromuscular problems. The report questions whether new safety standards announced by the USDA for young chickens and turkeys are sufficient, and recommends evaluating and tightening these standards over time.

    • Salmonella is the leading disease-causing bug overall, causing more than $3 billion in disease burden annually. In addition to poultry, Salmonella-contaminated produce, eggs and multi-ingredient foods all rank in the Top 10. The report recommends that the FDA and USDA develop a joint Salmonella initiative that coordinates efforts in a number of foods.

    • Four combinations in the Top 10 – Listeria in deli meats and soft cheeses, and Toxoplasma in pork and beef – pose serious risks to pregnant women and developing fetuses, causing stillbirth or infants born with irreversible mental and physical disabilities. The report recommends that agencies strengthen prevention programs for these pathogens and improve education efforts aimed at pregnant women.

    • Norovirus is the most common foodborne pathogen and is largely associated with multi-ingredient items that can become contaminated, often by service-industry workers who handle food. The researchers recommend strengthening state and local food safety programs through increased funding, training and adoption by states of the most recent FDA Food Code.

    • The report lists E. coli O157:H7 as the sixth pathogen in overall burden, with the majority due to contaminated beef and produce. The report recommends federal agencies continue to target E. coli O157:H7, due to the particularly devastating injuries it causes in small children, including kidney failure, lifetime health complications, and death.

    The report is available at: http://www.epi.ufl.edu/sites/www.epi.ufl.edu/files/RankingTheRisksREPORT.pdf
     

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  • Posted: August 24th, 2008 - 5:11pm by Doug Powell

    My friend and OK hockey player Scott Weese seems to be having fun with his Worms and Germs blog. It’s a great resource for pet ownership, especially aspects of zoonotic disease.

    Yesterday, Scott asked, are pregnancy and cats compatible? Amy, who’s six months pregnant, and I share our Manhattan home with two dogs and two cats (the cats are from Walkerton, Ontario, and made the trip to Kansas with me). Scott writes, and I didn’t know about the 24-hour infectious bit, that,

    “Cats are the only animal species that can spread Toxoplasma in their stool. Shedding rates in cats are quite low, but can be higher in cats that go outside, hunt or are fed raw meat. However, it takes 24 hours or more for Toxoplasma in stool to be infectious (that means that fresh stool cannot spread Toxoplasma). That key point greatly reduces the risk of transmission from cats.”


    Sure, if you clean the litter box regularly. That’s Amy with Crystal (right).
     

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